Sicily's capital city features a deep medley of culture with many noteworthy monuments.
Featured Cruises from Palermo, Sicily, Italy
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Palermo, Sicily, Italy
Palermo is an ancient port city that is filled with many palaces, cathedrals, and museums. A very walkable city, you can easily reach the historic center of Palermo on foot from the cruise port. Don’t be surprised if you come across Arab-influences (such as in architecture), as the Arabs once held a predominant influence over this city. It is a perfect mixture of European and Arab influences. There are numerous landmarks and interesting things to do in this city.
A great time to visit Palermo is between April and July, or between September and November, for the most ideal weather. Summer months (June, July, August) are great there, but they're also typically Palermo’s hottest months.
American Discount Vacations is proud to offer the best deals possible on all cruises from Palermo, Sicily, Italy. Backed by our "Low Price Guarantee," and powered by our team of expert travel agents, we're sure to exceed your expectations when booking your next cruise departing from Palermo, Sicily, Italy!
Destinations for Cruises from Palermo, Sicily, Italy
The following cruise destinations can be visited on a cruise from Palermo, Sicily, Italy. Select a destination to view the upcoming cruises that are available:
Make a selection below to view the cruises available during that month in that destination.
Pricing listed above is per person, based on double occupancy in the least expensive accommodations available, is subject to change, and may not reflect the most recent pricing (as pricing gets updated throughout the day). Prices include Required Cruise Fees & Expenses, as well as Government Taxes & Fees. Prices may not reflect discounts and special promotions that you may qualify for. Go to the Category selection step of the online booking process to view the live pricing and latest offers.
Cruise Lines with Cruises from Palermo, Sicily, Italy
The following cruise lines feature cruises leaving from Palermo, Sicily, Italy. Select a cruise line to view upcoming cruises that they're offering from Palermo, Sicily, Italy:
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Mainstream Cruise Lines
Value is a key feature of these popular cruise lines, as they offer lots of activities, entertainment and dining options, along with a variety of stateroom types. Some of the cruise lines in this category have ships with unique innovations like water slides, rock-climbing walls, ice-skating rinks, surfing simulators, bowling alleys, and boardwalks.
Their ships are usually anywhere from mid-sized to very large "mega" ships, accommodating thousands of guests. These ships give the feel of being in a large resort.
Mainstream cruise lines are a great option for just about everyone (including multi-generation families, and first-time cruisers), and typically have great youth programs.
During the cruise, entertainment may include Broadway productions, Vegas-style shows, comedians, and music. Some of these lines have select formal nights during the cruise. Specialty restaurants are becoming more and more common (some which have a cover charge for this type enhanced dining experience). Buffets are usually available throughout the day, besides room service, and the main dining room(s).
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Luxury Cruise Lines
When the finest cruise vacation is your top priority, this is the place to start.
On a luxury cruise line, guests experience highly personalized service, a more intimate (and usually formal) onboard experience, gourmet cuisine, well-appointed accommodations, and fantastic amenities. Many of these brands have smaller ships, allowing them to reach ports of call that the larger ships can't, which results in unique itineraries.
All of these brands feature a version of all-inclusive pricing, and some of them have ships with all-suite accommodations. Although these cruise lines are usually more expensive than the rest, they also provide their guests with so much more, resulting in a fantastic value when considering all that's included.
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Specialty Cruise Lines
These cruise lines offer a truly unique vacation experience, with a wide range of possible amenities and itineraries. Some are expedition cruise lines, others have sailing yachts or are coastal ships.
On these types of cruise lines, there's usually a focus on a specific destination or theme. Itineraries are usually very destination intensive, aided by the fact that they're able to reach many ports of call that larger ships can't.
Expedition cruise lines are a great fit for adventure-seeking travelers, featuring exciting destinations like the Galapagos Islands, Antarctica, and the Norwegian coast. During the cruise, there will usually be plenty of interesting lectures given by experts on the destination being visited. Often, shore excursions are included in the cost of the cruise. In fact, some of these cruise lines have all-inclusive pricing. There's a definite focus on the ship's surrounding scenery, as well as opportunities to view wildlife in their natural habitat. Small, but comfortable, ships are commonplace here, with anywhere from basic to very luxurious public spaces, cuisine, and accommodations (depending on the cruise line and ship).
Sailing Yachts, sail-assisted motor ships, offer a really unique vacation experience. Accommodations and cuisine on these intimate vessels can be anywhere from good to fantastic, depending on the cruise line. Destinations offered by these cruise lines may include the Caribbean, Europe, Panama Canal, Tahiti, and Costa Rica.
Costa Cruises enjoys the reputation of being Europe’s number one cruise line. This Italian company has a large fleet that sails Caribbean, Mediterranean, Northern Europe, South America, Asia, Indian Ocean, Middle East, Baltic and Russia, and Transatlantic itineraries. Spa accommodations are available on several of the newer Costa ships, and there are a wide range of things to do as you Cruise Italian Style with them.
MSC Cruises is the world's third-largest cruise line with a strong and growing presence in North America and is committed to achieving net zero greenhouse gas emissions by 2050. With 23 ships and over 250 destinations to choose from, guests can enjoy beautifully designed ships with a diverse guest mix. MSC Cruises sails year-round from Miami, Orlando (Port Canaveral), New York City, and Galveston starting November 2025. Many itineraries include late-night and overnight stays at Ocean Cay MSC Marine Reserve, the only private island marine reserve in The Bahamas. For guests wanting privacy and luxury, most U.S. ships offer the MSC Yacht Club, an exclusive sanctuary at the top of the ship only accessible by key card. MSC Cruises is a great vacation choice for families, with many activities and expansive kids' clubs for kids of all ages. In April 2025, MSC Cruises' newest flagship, MSC World America, will sail from Miami to the Caribbean. Beauty and discovery await with MSC Cruises.
With over 70 years of expertise in extraordinary remote destinations, Swan Hellenic offers a truly unique luxury cruise experience with its brand-new fleet of expedition ships. The company focuses on guests' preferences and needs, environmental safety, and once-in-a-lifetime adventures, proposing enriching cultural expeditions with unforgettable itineraries to Iceland, Norway, Antarctica, Lands of the Celts, Lands of the Vikings, and more.
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Things to do near Palermo, Sicily, Italy
These are just a few of the more popular tourist attractions in Palermo, along with a brief description:
♦ Teatro Massimo
Art and culture lovers are certain to be fascinated by Teatro Massimo, Palermo’s grand opera house. Located right in Piazza Verdi, it is one of Europe’s largest opera houses, able to accommodate over 1,300 guests. The building features a neo-classical façade with an art—nouveau interior, certain to aesthetically please anyone who is interested in architecture. For a small fee, you can tour the inside of this landmark. If you’re lucky, you might get to catch the orchestra during rehearsal!
♦ Cattedrale di Palermo
Also known as Palermo Cathedral, this Roman Catholic church is one of the most ornate churches in the city. Despite many exterior modifications over the centuries, it remains a great example of the Arab influences that once dominated Palermo. For a small fee, you can visit the royal tombs located in the church’s crypt, as well as access the rooftop. The panoramic views from the top are simply spectacular, providing you with a breathtaking view of the city center.
♦ Catacombe dei Cappuccini
If you’re looking for a truly unique activity before or after your cruise from Palermo, consider checking out this eerie crypt, where you can get up close with over 7,500 mummies and skeletons. Many are still dressed in original clothing, and are relatively well-preserved. This is a great activity if you’ve seen most of the landmarks in Palermo and the surrounding cities.
Average Monthly Weather for Palermo, Sicily, Italy
Temperature
Average monthly high and low temperatures. Values are in Fahrenheit (switch to Celsius):
The information above is provided for informational purposes only. Monthly statistics are based on the most recent instance of that month. Weather is subject to change and cannot be guaranteed. The data is provided by a third-party and we accept no liability regarding its accuracy.