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Wonderful City!
St. Louis, MO Highlights
Wonderful City!
One of the United States' most iconic monuments, the Gateway Arch welcomes everyone into St. Louis.
Destination Calendar
Cruise Lines

St. Louis, MO

St. Louis is a wonderful riverfront town that is filled with scenic beauty. It is also a great place to take an Upper Mississippi cruise from. Highlighted by the famous Gateway Arch, St. Louis is a major U.S. city that is certain to make your next U.S. river cruise even more enjoyable. Cruises from St. Louis are typically available from July to October. There are also many river cruises that include St. Louis as a destination port in their itinerary, rather than as a departure port.

Viking River Cruises, American Cruise Lines, and American Queen Steamboat Company all offer cruises from St. Louis. Contact us for information regarding pre-cruise packages that allow you to stay in the city for a night before your cruise from St. Louis. This is a very convenient way to enjoy St. Louis on your own time, making more memories than you can imagine!

American Discount Vacations is proud to offer the best deals possible on all cruises from St. Louis, MO. Backed by our "Low Price Guarantee," and powered by our team of expert travel agents, we're sure to exceed your expectations when booking your next cruise departing from St. Louis, MO!

Destinations for Cruises from St. Louis, MO

The following cruise destinations can be visited on a cruise from St. Louis, MO. Select a destination to view the upcoming cruises that are available:

Destination Calendar
Make a selection below to view the cruises available during that month in that destination.
Pricing listed above is per person, based on double occupancy in the least expensive accommodations available, is subject to change, and may not reflect the most recent pricing (as pricing gets updated throughout the day). Prices may not reflect discounts and special promotions that you may qualify for. Go to the Category selection step of the online booking process to view the live pricing and latest offers. Taxes, fees, and port expenses are additional (and are displayed on the Search Results step (and the steps that follow it) in the online booking process.

Cruise Lines with Cruises from St. Louis, MO

The following cruise lines feature cruises leaving from St. Louis, MO. Select a cruise line to view upcoming cruises that they're offering from St. Louis, MO:

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River Cruise Lines

Becoming more and more popular, a river cruise is an immerse and destination-focused vacation experience, on a small and luxurious vessel.

River cruises sail through the inland waterways of some of the world's most interesting vacation destinations (i.e. Europe, Asia, the Middle East, and North America), and provide their guests with a greater opportunity to spend time visiting more unique ports of call than a traditional cruise typically would.

Because the destination is the star of a river cruise, (typically guided) shore excursions are included at no additional charge by many River cruise lines. There are usually many interesting lectures given during the cruise, by experts on the history and culture of the region being visited.

Among the famous rivers that one may take a river cruise on are the Rhine, Mississippi, Seine, Danube, Mekong, Nile, Yangtze, Amazon and Douro.

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Specialty Cruise Lines

These cruise lines offer a truly unique vacation experience, with a wide range of possible amenities and itineraries. Some are expedition cruise lines, others have sailing yachts or are coastal ships.

On these types of cruise lines, there's usually a focus on a specific destination or theme. Itineraries are usually very destination intensive, aided by the fact that they're able to reach many ports of call that larger ships can't.

Expedition cruise lines are a great fit for adventure-seeking travelers, featuring exciting destinations like the Galapagos Islands, Antarctica, and the Norwegian coast. During the cruise, there will usually be plenty of interesting lectures given by experts on the destination being visited. Often, shore excursions are included in the cost of the cruise. In fact, some of these cruise lines have all-inclusive pricing. There's a definite focus on the ship's surrounding scenery, as well as opportunities to view wildlife in their natural habitat. Small, but comfortable, ships are commonplace here, with anywhere from basic to very luxurious public spaces, cuisine, and accommodations (depending on the cruise line and ship).

Sailing Yachts, sail-assisted motor ships, offer a really unique vacation experience. Accommodations and cuisine on these intimate vessels can be anywhere from good to fantastic, depending on the cruise line. Destinations offered by these cruise lines may include the Caribbean, Europe, Panama Canal, Tahiti, and Costa Rica.

American Cruise Lines
  • River / Specialty Cruise Line
  • Ships: 21 (90 - 180 Guests)
  • Destination Immersion®
  • Gratuities Included
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Viking River Cruises
  • River Cruise Line
  • Ships: 66 (52 - 386 Guests)
  • Shore Excursions & Wi-Fi Included
  • Wine & Beer Included at Lunch &
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Things to do near St. Louis, MO

These are just a few of the more popular tourist attractions in St Louis, along with a brief description:

♦ Gateway Arch National Park

You can’t miss this park, considering that the Gateway Arch that welcomes visitors is the tallest building in Missouri. This 90-acre park is part of the U.S. National Register of Historic Places and features the arch and St. Louis’ Old Courthouse, as well as a museum. There is an observation center at the top of the arch, which you can reach by a tram system. Beneath the arch, there is a museum where you can learn about fascinating topics in U.S. history (such as the westward expansion) as well as about the arch’s construction.

♦ St. Louis Zoo

If you love animals and have some time before or after your cruise from St. Louis, the St. Louis Zoo is definitely worth checking out! This zoo features some truly unique exhibits, such as a touch pool with sharks and stingrays, a children’s zoo (where staff bring out some of the animals for kids to get a closer look), and animals from all over the world! Admission to this zoo is free, although certain exhibits require a cover charge. Either way, this is a great activity for families, or for those who are interesting in seeing some really unique animals! Admission fees are subject to change. Please verify information directly with St. Louis Zoo prior to your trip.

♦ Missouri Botanical Gardens

Also known as “Shaw’s Garden,” these botanical gardens are the second largest in the country, with over 6.6 million specimens in its herbarium alone! Among some of the attractions here are the Tower Grove House (a beautiful Victorian country home), Climatron (the world’s first dome-shaped greenhouse), a biblical garden (featuring many of the plants mentioned in the Bible), and a Butterfly House on top of many relaxing water features, statues, and reflecting pools. This is a great place to spend some time walking around and exploring before or after your cruise.

Average Monthly Weather for St. Louis, MO


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The information above is provided for informational purposes only. Monthly statistics are based on the most recent instance of that month. Weather is subject to change and cannot be guaranteed. The data is provided by a third-party and we accept no liability regarding its accuracy.